Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin
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منابع مشابه
Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore.
Staphylococcal leukocidin pores are formed by the obligatory interaction of two distinct polypeptides, one of class F and one of class S, making them unique in the family of beta-barrel pore-forming toxins (beta-PFTs). By contrast, other beta-PFTs form homo-oligomeric pores; for example, the staphylococcal alpha-hemolysin (alpha HL) pore is a homoheptamer. Here, we deduce the subunit compositio...
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INTERACTIONS between bacterialexotoxinsandadrenocortical hormoneshave been described by a number of investigators (Zwemer and Jungeblut, 1935; Greene, Ambrus and Gershenfeld, 1953 ; Seneca, Kupyn and Johnson, 1957 ; Orsi, Poggioliiii and Terzani, 1962). Seneca et al. (1957) reported that incubation of prednisolone hemisuccinate with " micrococcal " toxin reduced its haemolytic titre four-fold. ...
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ژورنال
عنوان ژورنال: Nature Microbiology
سال: 2018
ISSN: 2058-5276
DOI: 10.1038/s41564-018-0159-x